Non-parametric bootstrap and permutation resampling-based multiple testing procedures for controlling the family-wise error rate (FWER), generalized family-wise error rate (gFWER), tail probability of the proportion of false positives (TPPFP), and false discovery rate (FDR). Single-step and step-wise methods are implemented. Tests based on a variety of t- and F-statistics (including t-statistics based on regression parameters from linear and survival models) are included. Results are reported in terms of adjusted p-values, confindence regions and test statistic cutoffs. The procedures are directly applicable to identifying differentially expressed genes in DNA microarray experiments.
| Author | Katherine S. Pollard, Yongchao Ge, Sandra Taylor, Sandrine Dudoit |
| Maintainer | Katherine S. Pollard |
To install this package, start R and enter:
source("http://bioconductor.org/biocLite.R")
biocLite("multtest")
Vignettes (Documentation) |
Package Downloads |
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| biocViews | |
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| Depends | R, methods, Biobase, survival |
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| License | LGPL |
| URL | |
| dependsOnMe | ABarray, LMGene, OCplus, SAGx, aCGH, adSplit, globaltest, siggenes, webbioc |
| suggestsMe | BiocCaseStudies, GOstats, GSEAlm, GeneSelector, GlobalAncova, XDE, annaffy, ecolitk, maigesPack, oneChannelGUI, pcot2, safe, topGO, xcms |